The Sharples research group were the first internationally to show human skeletal muscle possesses an epigenetic memory of muscle growth (hypertrophy) after exercise.
The research group investigates if skeletal muscle possesses a ‘memory’ within its DNA (in the form of epigenetic imprints) following exercise, and after muscle growth, wasting or ageing. They also investigate how novel molecules affect skeletal muscle growth and loss.
The lab currently has 10 million NOK funding from the Research Council of Norway and other sources to investigate if human skeletal muscle remembers periods of wasting with age.
You can learn about the different aligned research areas here: